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Resource Library / Simultaneous Determination of Coproporphyrin-I and Coproporphyrin-III in Human Plasms and Human Urine Using LC-MS/MS

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Simultaneous Determination of Coproporphyrin-I and Coproporphyrin-III in Human Plasms and Human Urine Using LC-MS/MS

In this study, we developed and validated an LC-MS/MS method for the simultaneous determination of CP-I and CP-III in human plasma with the lowest LLOQ limit.

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Simultaneous quantification of total antibody and antibody-conjugated drug for XMT-1522 in human plasma using immunocapture-liquid chromatography/mass spectrometry
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Simultaneous quantification of total antibody and antibody-conjugated...
XMT-1522, an antibody-drug conjugate (ADC) currently in Phase I clinical development, repr...
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Quantitation Of Four Chiral Drug Compounds Simultaneously Using Normal Phase LC MS MS Equipped With An APPI Ion Source
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Quantitation Of Four Chiral Drug Compounds Simultaneously Using...
Chiral separation is important but also challenging for bioanalysis of the antifungal drug...
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Development and Validation of an LC-MS.MS Method for the Simultaneous Quantitation of Fifteen Bile Acids in Human Serum
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Development and Validation of an LC-MS.MS Method for the Simultaneous...
In this study, we discuss the development and validation of an LC-MS/MS method for the qua...
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An Ultrasensitive LC-APPI-MS/MS Method for Simultaneous Determination of Ciclesonide and Active Metabolite Desisobutyryl-Ciclesonide inHuman Serum and Its Application to a Clinical Study
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An Ultrasensitive LC-APPI-MS/MS Method for Simultaneous Determination...
An Ultrasensitive LC-APPI-MS/MS Method for Simultaneous Determination of Ciclesonide and A...
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Immunocapture-liquid Chromatography/Mass Spectrometry in Simultaneous Quantification of Total Antibody and ADC for XMT-1522 in Human Plasma
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Immunocapture-liquid Chromatography/Mass Spectrometry in Simultaneous...
Immunocapture-liquid Chromatography/Mass Spectrometry in Simultaneous Quantification of To...
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Development and validation of LC-MS/MS methods for the quantification of the novel anticancer agent guadecitabine and its active metabolite β‑decitabine in human plasma, whole blood and urine
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Development and validation of LC-MS/MS methods for the quantification...
Guadecitabine (SGI-110), a dinucleotide of β‑decitabine and deoxyguanosine, is currentl...
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Validation of a Low-Volume Plasma LC-MS/MS Method Using a CapillaryMicrosampling (CMS) Technique
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Validation of a Low-Volume Plasma LC-MS/MS Method Using a...
With the development of more sensitive instrumentation, there is a greater need for smalle...
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Qualification of the Quanterix Phospho-Tau 217 (pTau-217) assay using the Simoa HD-X platform
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Qualification of the Quanterix Phospho-Tau 217 (pTau-217) assay using...
Alzheimer’s disease (AD) is a neurodegenerative disorder which stands as one of the most...
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High Throughput Sample Analysis Using Gyrolab
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High Throughput Sample Analysis Using Gyrolab
In this case study, Frontage successfully completes the method development and validation ...
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Preclinical Drug Screening Using Gyrolab
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Preclinical Drug Screening Using Gyrolab
In this case study, we share how Frontage used Gyrolab to conduct a Sponsor's study effici...
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Neurofilament Light Chain: Method Validation of Quantitation Using the Quanterix Simoa™ Platform and Potential Applications
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Neurofilament Light Chain: Method Validation of Quantitation Using...
In this study, we quantify Neurofilament Light Chain (NF-L) in human plasma, serum, and CS...
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Surrogate Analyte Approaches in Bioanalysis using LC-MS-MS
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Surrogate Analyte Approaches in Bioanalysis using LC-MS-MS
Surrogate matrix has been widely used in bioanalysis, especially for endogenous compounds ...
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