Technology Platforms

Flow Cytometry

Technology Platforms

Supporting Comprehensive Quality Assay Development

Flow cytometry or FACS enables cell population-specific measurement of signaling changes. Frontage supports sponsors with de novo assay development and subsequent compound screening using cell lines, donor PBMC, and whole blood. 

Some representative assays we have developed include: 

  • CD4+ / CD8+ T cell population in patient PBMC
  • GM-CSF stimulated pSTAT5 in lysed whole blood
  • Interferon alpha stimulated pSTAT1 in lysed whole blood
  • IL-2 stimulated T cell proliferation
  • IL-2 stimulated pSTAT5 in PBMC
  • IL-4 stimulated pSTAT6 in PBMC
  • IL-6 stimulated pSTAT3 in PBMC

Uses of Flow Cytometry