- Metabolic Stability
- CYP Interaction
- Permeability & Transporters
- Physicochemical Properties
- Protein Binding
Discovery PK and Toxicology
Frontage’s experienced staff and state-of-the-art instrumentation deliver data you can trust. Count on Frontage Laboratories for reliability. From method development or transfer and validation to sample analysis and reporting, Frontage’s bioanalytical team has earned a reputation for consistent and high-quality delivery, project after project. Our bioanalytical expertise extends to combined small and large molecules such as protein, antibody, antibody-drug conjugates as well as biomarker analysis for small molecule drug candidates.
Frontage’s CMC portfolio of services spans pre-formulation, drug product formulation development, analytical method development and validation, GLP batches, GMP clinical trial materials (manufacturing, labeling, packaging, and distribution), scale up, pilot and pivotal/registration batches, and commercial manufacturing (to be ready Q3 2024).
Our formulation development experience and capabilities cover a wide range of dosage forms for IND, NDA, ANDA and 505(b)(2) filings.
Frontage Global Drug Discovery Services (GDDS) offers a complete line of chemistry services. Our hit and lead generation (Hit-to-Lead), lead optimization, process chemistry and manufacturing, and customer synthesis enables speedy advancement of compounds from labs to clinics.
Frontage Global Drug Discovery Services (GDDS) offers a comprehensive compound screening platform with a wide range of enzymatic and cell-based assays. Our experienced team of scientists routinely develop and validate new screening assays to support compound selection and advancement. We believe in a customer centric approach, providing real-time communication and reliable consultation to Sponsors.
Frontage Global Drug Discovery Services (GDDS) offers a wide range of in vitro and in vivo pharmacological models, such as oncology, metabolic diseases and inflammation. We believe in a customer-centric approach providing real-time communication and reliable consultations to Sponsors.
Frontage Global Drug Discovery Services (GDDS) offers a full spectrum of in vitro ADME assays for small molecule drug discovery and preclinical development. Our strong focus on lab operations, automation, and project management enables efficient delivery and unparalleled quality. We believe in a customer-centric approach providing real-time communication and reliable consultations to Sponsors.
Frontage staff are dedicated to providing customized laboratory and computational workflows that enable cost-effective and rapid production of informative data sets, leading to advances in biomarker discovery, drug discovery, and basic medical research for its clients.
Hosted by ISSX, Frontage's own Dr John Kapeghian discusses the "Cost Effective and Efficient Progression of Lead Drug Candidates to First in Human Studies in the Two Largest Economies in the World: USA and China."