In Vitro Services

Metabolite Profiling and Identification

In Vitro Services

The identification of metabolic pathways of drug candidates play a key role in drug discovery, pre-clinical, and clinical development. 

Metabolite identification studies are critical in supporting the development of your drug candidate. By better understanding the metabolic profile of a drug, insights can be gained relevant to the pharmacokinetics and safety of the compound.


  • Metabolic soft spot determination 
  • Cross-species metabolite characterization using liver microsomes and hepatocytes with unlabeled and radiolabeled test articles 
  • Mechanistic studies (reactive metabolites, mechanism of chiral inversion, etc.)

LC/UV Metabolite Profiles of a Test Compound in Hepatocytes

Discover the following In Vitro services at Frontage