- Metabolic Stability
- CYP Interaction
- Permeability & Transporters
- Physicochemical Properties
- Protein Binding
Discovery PK and Toxicology
Frontage offers a series of early discovery services that help sponsors with target discovery and validation, honing down on their lead compounds for development.
At Frontage, we offer a comprehensive portfolio of drug candidate evaluation services including DMPK, Safety and Toxicology, and Bioanalytical related services.
Our portfolio of Product Development and CMC services spans from drug discovery to the post approval phase, including lead compound quantification and analytical testing.
With over 20 years of experience in the execution of comprehensive Phase I-IIa studies, Frontage Clinical Services has completeed more than 20 studies.
Our next generation central laboratories provide a comprehensive range of laboratory testing, global logistics and project management services.
Frontage’s experienced staff and state-of-the-art instrumentation deliver data you can trust. Count on Frontage Laboratories for reliability. From method development or transfer and validation to sample analysis and reporting, Frontage’s bioanalytical team has earned a reputation for consistent and high-quality delivery, project after project. Our bioanalytical expertise extends to combined small and large molecules such as protein, antibody, antibody-drug conjugates as well as biomarker analysis for small molecule drug candidates.
Frontage introduces a new ultrasensitive assay for the quantitative determination of pTau217 in human plasma, serum, and cerebrospinal fluid (CSF), one of the most promising blood-based biomarkers of Alzheimer’s disease.
Frontage offers various genetic toxicology services. Genotoxicity assessment is essential for the safety assessment of all types of substances, from pharmaceuticals, to food and agrochemical products. In general, the assessment of genotoxic hazards to humans follows a step-wise approach, beginning with a basic battery of in vitro tests followed in some cases by in vivo testing.
We know that to attract the best candidates we have to provide a stimulating and challenging work environment that gives our employees the opportunity to meet their career goals. We also recognize the need to offer a competitive benefits package for our employees and their families.Learn More