Frontage’s discovery team is comprised of experienced medical chemists, biologists,and DMPK scientists that help Sponsors generate hits and leads. We profile, optimize, and advance the compounds to an IND candidate.
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Frontage supports early drug discovery with various immunoassays for proteins and therapeutic antibodies to support pharmacokinetics/toxicokinetics (PK/TK), pharmacodynamics (PD), and biomarkers analysis.
In this eBook, we navigate the landscape of biomarker discovery through genomic profiling, exploring technologies, methods, and applications. We hope this collection of articles creates an appreciation for the wide scope of using sequencing assays for biomarker discovery, drug development, and beyond.
As more and more platforms and instruments come to play in the biomarker research, the method development and validation for biomarkers become more and more complex. Best regulatory practice in analyzing biomarkers to support drug development is expected, but deciding which regulation to follow has not been consistent.