Early Discovery Services

Frontage’s qualified discovery team provides access to highly experienced chemists and provides scalable FTE to support sponsors on their drug discovery journey. Our early discovery services support your compound from hit screening and identification to drug candidate selection and beyond. Given that an average drug can take 10-15 years and cost nearly USD$2 billion to go to market, it is highly recommended to make scientific investments in the early phase discovery stage. Thorough testing early in the discovery phase allows sponsors to make educated decisions about compounds to advance in the development process while saving time and money later.

 

Early discovery at Frontage offers an impressive comprehensive package of solutions: 

• Medicinal Chemistry 
• ADME 
  • Metabolic Stability 
  • CYP Interaction 
  • Permeability and Transporters 
  • Physicochemical Properties 
  • Protein Binding 

• Biology
  • Compound Screening
  • Flow Cytometry 

• PK and Toxicology 
  • Formulation Testing 
  • Screening PK (mouse/rat)  
  • Mini Ames 

• hERG 

  Contact us to discuss your early discovery projects.