Discovery
Medicinal Chemistry Services
Discovery ADME
- Metabolic Stability
- CYP Interaction
- Permeability & Transporters
- Physicochemical Properties
- Protein Binding
Exosomes are microscopic vesicles which are secreted by almost all cell types and are also present in almost every biological fluid. While exosomes were originally considered a mechanism to discarding unwanted cellular debris, today these nano-sized membrane vesicles are valued as highly relevant therapeutic targets for many diseases due their roles in disease transmission, intercellular cross-talk, angiogenesis, and inflammation. Specifically, exosomes are implicated in the progression of many diseases. Frontage provides comprehensive, end-to-end exosome isolation and purification services.
At Frontage, our Genomics team can isolate exosomes using a wide variety of techniques particularly well-suited for large volume samples.
Frontage can identify the size distribution and concentration of exosomes present in the biosamples prior to subsequent analysis. This quantitative and visual analysis provide a first characterization of the exosomes potentially involved in pathological processes of diseases including tumor and neurodegenerative diseases.
Investigations of exosome-bound genetic information, which can include long and small RNAs, can be used to identify cell– or tissue-specific markers and detect diagnostic and prognostic biomarkers useful for patient stratification or the determination of non-responders.
Frontage provides a comprehensive solution for exosomal RNA profiling.
Frontage offers characterization and quantitation of exosomal RNA of small and long RNA.
Our RNA sequencing services use a combination of state-of-the-art equipment that provides quick and accurate results for your RNA profiling projects.
Learn MoreOur customized laboratory and computational workflows enable cost-effective and rapid production of informative sequencing data sets.
Learn MoreOur Genomics team has extensive experience with a wide array of genomics services for pharmaceutical and clinical research in gene and cell therapy.
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