Small Molecule Bioanalysis / Mass Spectrometry

Our laboratories are equipped with state-of-the-art bioanalytical instruments and software programs for the efficient handling of challenging bioanalytical projects. We offer a broad array of small molecule bioanalysis services.

Our Small Molecule Bioanalysis Services Include:

• Method development, transfer, and validation
• Sample Analysis
• Nonclinical toxicokinetic /pharmacokinetic screening
• Clinical PK/bioavailability studies
• Bioequivalence studies
• Therapeutic drug monitoring studies
• Drug-drug interaction studies
• Protein binding studies
• Tissue analysis

Our expertise extends to projects that combine small and large-molecule bioanalytical activities such as protein, antibody, antibody-drug conjugates, and biomarker analysis for small-molecule drug candidates.

Request a quote for your small molecule bioanalysis.

From method development or transfer and validation to sample analysis and reporting, Frontage’s bioanalytical team has earned a reputation for consistent and high-quality delivery, project after project. With over 66 LC-MS/MS instruments available for methods development, validation, and sample analysis, we have the capacity and expertise to meet study timelines.

Expertise in a Wide Range of Techniques and Processes

Method Development, Transfer, and Validation

• Small Molecules
• Peptides
• Proteins
• Labile
• PEG-ylated
• Liposomal
• ADC’s
• Oligo’s
• Chiral
• Deuterated
• Elemental (Metals)
• Nicotine
• All biological matrices

Sample Analysis

• Preclinical PK/TK and All Clinical Studies
• DDI
• BA
• BE
• Protein binding studies
• Biomarker studies
• Pediatrics
• CMS/DBS
• Tissue

Quantitation of Complex Compounds

At Frontage, we support clients with challenging and unique studies. We have extensive experience with Liposomal and encapsulated drugs, PEG-ylated compounds, oligos, ADC, ADA, and Mab.