Formulation Testing

Delivering confidence in early product formulation

Formulation Testing

In pre-clinical pharmacokinetic (PK) and toxicokinetic (TK) studies, formulations play a critical role to ensure test articles are completely dissolved for intravenous administration and properly absorbed for oral or other routes of administration. Frontage has helped many companies in formulation development using different strategies based on the properties of the new API. Our primary approaches are:

  • The evaluation of pH effect 
  • Selection of co-solvents 
  • Selection of surfactants 
  • Complex formation using cyclodextrin or its derivatives 
  • Lipid-based formulations 
  • Combinations of multiple strategies above 

Talk to our preclinical formulation experts about your compounds.