Surrogate matrix has been widely used in bioanalysis, especially for endogenous compounds analysis. Surrogate analyte approaches, on the other hand, are only occasionally employed in bioanalysis, but play a significant role and serve as a useful tool for the quantitation of various analytes, ranging from small molecular biomarkers to large molecule biological entities. This webinar will give a brief review of the surrogate analyte approaches during bioanalysis using LC-MS platform, from both scientific and regulatory perspectives. A few case studies will be discussed in detail laying out the challenges, and approaches to tackle these challenges.
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In this case study, Frontage successfully completes the method development and validation under the Sponsor's pressing timelines, while providing high quality, and reproducible data with an ISR passing rate of over 90%.
In this case study, we share how Frontage used Gyrolab to conduct a Sponsor's study efficiently saving precious sample volumes.
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