Discovery
Medicinal Chemistry Services
Discovery ADME
- Metabolic Stability
- CYP Interaction
- Permeability & Transporters
- Physicochemical Properties
- Protein Binding
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webinar
ADC Webinar: "Bioanalytical Strategies for PK Analysis of Antibody Drug Conjugate (ADC) Therapeutics using LC-HRMS & LC-MS/MS"
ADCs (Antibody Drug Conjugates) combine the best of two modalities, toxic efficacy, and antibody specificity. The result is an improved therapeutic window with fewer side effects. However, the bioanalytical requirements for PK analysis also require a multifaceted approach. Here-in we describe various mass spectrometry-based strategies Frontage has successfully applied in the bioanalysis of ADCs for clinical and preclinical studies.
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