Midazolam is a widely used central nervous system depressant. It is used for the treatment of insomnia, seizure, and induction of sedation or amnesia for operations. Midazolam is metabolized by cytochrome CYP3A. It is a widely used probing drug for evaluation of CYP3A activity in drug-to-drug interaction (DDI) studies. 379

Development and Validation of an Ultra Sensitive LC-MS/MS Method for…

Midazolam is a widely used central nervous system depressant. It is used for the treatment of insomnia, seizure, and induction of sedation or amnesia for operations. Midazolam is metabolized by cytochrome CYP3A. It is a widely used probing drug for evaluation of CYP3A activity in drug-to-drug interaction (DDI) studies.