Fascin is an actin-bundling protein that has been linked to tumor cell migration, invasion, metastasis, disease progression and mortality, thus serving as a novel cancer biomarker. In this paper, we develop and validate an LC-MS/MS method for the quantification of fascin proteins in human serum.

In this infographic, we share the emerging technologies beyond monoclonal antibodies and the bioanalytical methods to support the new technologies.

In this study, we quantify Neurofilament Light Chain (NF-L) in human plasma, serum, and CSF on the Quanterix Simoa™ Platform using a commercial Simoa NF-Light Assay Kit provided by Quanterix Corporation. We also discuss potential applications.