Resource Library / Duplex Sequencing: A Powerful Tool for In Vivo Gene Mutation

Duplex Sequencing: A Powerful Tool for In Vivo Gene Mutation

Discover our EMGS 2025 poster showcasing how Duplex Sequencing (ecNGS) reveals the genotoxic profile of 5-(2-Chloroethyl)-2'-deoxyuridine (CEDU). This study demonstrates ecNGS as a powerful tool for detecting ultra-rare mutations and characterizing mutation spectra in bone marrow and liver, providing deeper mechanistic insight into compounds with atypical genotoxic profiles.

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