In this abstract, we discuss a Phase 1, open-label, two-period, sequential study to assess the effects of carvedilol phosphate on the pharmacokinetics of colchicine oral solution in healthy adult subjects.

The purpose of this study was to develop a better model to improve the quality of ddPCR assay validation, involving how to improve the reliability of accuracy, precision, and sensitivity.

To ensure good data yield, there are challenges encountered during NGS operations, especially with poor quality RNA or DNA material, which is a common scenario for clinical samples. In this poster, we showcase three key tricks during the NGS operations to generate consistent data with high quality.