Bioanalysis of antibody-drug conjugates (ADCs) by LC/MS: challenges and solutions

In this eBook, we explore the various ways LC-MS is utilized for the bioanalysis of ADCs and the strategies used for ADCs in biotherapeutics and clinical development.

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Bioanalysis of antibody-drug conjugates (ADCs) by LC/MS: challenges and solutions

Resources to Consider

Accurate determination of drug-to-antibody ratio of interchain...

Characterization of Positional Isomers of Interchain Cysteine Linked...

Characterization of Interchain Cysteine Linked Antibody Drug...

Bioanalytical Strategies for PK Analysis of Antibody-Drug Conjugates...

ACS 2025: Quantitative Analysis of Cyclic Peptide by LC MS/MS with...

Addressing the Increasing Needs of Data Integrity by Implementing the...

Quantitative Assessment of mRNA Drug Biological Activity by...

Quantitative Analysis of Oligonucleotide by Ion Paring Reversed-Phase...

IN Vitro Assessment of the inhibition of Human Organic Anion...

A Hybrid Trial Approach by Combining 13C8-Lableded & Radiolabeled...

Quantitative Analysis of Antibody Conjugate Payload by LC MS/MS...

Achieving sensitive and specific oligonucleotide quantification by...