At Frontage, we provide comprehensive central lab services, including a range of laboratory testing, histology and pathology services, sample management, and global distribution. See our brochure about next-generation central lab services.
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Regulated preclinical developmental and reproductive toxicity (DART) studies using mammalian research models are an important step to take before initiating clinical trials. Frontage’s scientists have over 20 years of experience running DART studies with knowledge of accurately estimating test doses, showing formulation stability, and expertise in animal handling. Our labs have the extensive capacity to run many studies, helping our sponsors meet their timelines with uncompromising quality.
At Frontage, we offer extensive drug metabolism and pharmacokinetic capabilities for new chemical entities and compounds in development. We provide rapid turnaround of high-quality key DMPK data sets to support critical decisions in advancing potential therapeutic agents for further development. Our highly trained scientific staff applies state-of-the-art techniques and best-in-class approaches to provide broad and in-depth expertise/advice to clients on appropriate study designs, execution of studies, and interpretation of the data. DMPK studies can provide critical data during discovery and development of pharmaceutical and agrochemical products. Frontage’s DMPK services, performed in accredited facilities, can help support lead drug candidate or chemical selection, or help you meet specific regulatory requirements.
Drug transporters can be major determinants of pharmacokinetics, drug-drug interactions, and the safety and efficacy of drugs. At Frontage, we have extensive experience in transporter research. We offer comprehensive transporter services to support projects from discovery to development, including screening and full characterization in both uptake and efflux transporter.