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Cellular and gene therapies involve the delivery of genetic material to manipulate an individual’s cell for the treatment of different diseases including cancers and inherited disorders. With the number of gene therapy products in development increasing, bioanalytical methods are playing an important role in ensuring the success of these novel therapies.
As potential cell and gene therapies are investigated, it is essential to use bioanalytical methods to quantify the DNA, the vector and the expressed gene moieties to gain a complete understanding of PK, PD and safety.
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