Discovery
Medicinal Chemistry Services
Discovery ADME
- Metabolic Stability
- CYP Interaction
- Permeability & Transporters
- Physicochemical Properties
- Protein Binding
Assay Results
IFN-γ, IL-10, IL-1α and IL-1β -
(Matrix: Human Serum)
Analytes:
IFN-γ, IL-10, IL-1α and IL-1β
Matrix:
Human Serum
Assay Range:
IFN-γ: 0.170 pg/mL -4000 pg/mL
IL-10: 0.230 pg/mL - 5530 pg/mL
IL-1α: 0.0800 pg/mL - 1880 pg/mL
IL-1β: 0.0600 pg/mL - 1530 pg/mL
Sample Volume:
35 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
ELLA
IFN-γ, IL-10, IL-1β, IL-2, IL-4, IL-6, IL-8 and TNF-α -
(Matrix: Human Serum)
Analytes:
IFN-γ, IL-10, IL-1β, IL-2, IL-4, IL-6, IL-8 and TNF-α
Matrix:
Human Serum
Assay Range:
IFN-γ: The LLOQ is 1.638 pg/mL (3.276 pg/mL in human serum) and the ULOQ is
1000.000 pg/mL (2000.000 pg/mL in human serum);
IL-1β: The LLOQ is 0.301 pg/mL (0.602 pg/mL in human serum) and the ULOQ is
459.200 pg/mL (918.400 pg/mL in human serum);
IL-2: The LLOQ is 0.724 pg/mL (1.448 pg/mL in human serum) and the ULOQ is
1104.000 pg/mL (2208.000 pg/mL in human serum);
IL-4: The LLOQ is 0.117 pg/mL (0.234 pg/mL in human serum) and the ULOQ is
178.400 pg/mL (356.800 pg/mL in human serum);
IL-6: The LLOQ is 0.381 pg/mL (0.762 pg/mL in human serum) and the ULOQ is
580.800 pg/mL (1161.600 pg/mL in human serum);
IL-8: The LLOQ is 0.291 pg/mL (0.582 pg/mL in human serum) and the ULOQ is
444.000 pg/mL (888.000 pg/mL in human serum);
IL-10: The LLOQ is 0.195 pg/mL (0.390 pg/mL in human serum) and the ULOQ is
297.600 pg/mL (595.200 pg/mL in human serum);
TNF-α: The LLOQ is 0.468 pg/mL (0.936 pg/mL in human serum) and the ULOQ is
285.600 pg/mL (571.200 pg/mL in human serum);
Sample Volume:
80 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IFN-γ, IL-10, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-12p70, IL-13 and TNF-α -
(Matrix: Human Serum)
Analytes:
IFN-γ, IL-10, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-12p70, IL-13 and TNF-α
Matrix:
Human Serum
Assay Range:
IFN-γ: 0.37–938 pg/mL
IL-1β: 0.05–375 pg/mL
IL-2: 0.09–938 pg/mL
IL-4: 0.02–158 pg/mL
IL-6: 0.06–488 pg/mL
IL-8: 0.07–375 pg/mL
IL-10: 0.04–233 pg/mL
IL-12p70: 0.11–315 pg/mL
IL-13: 0.24–353 pg/mL
TNF-α: 0.04–248 pg/mL
Sample Volume:
80 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL12p70, and TNF-α -
(Matrix: Human Serum)
Analytes:
IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL12p70, and TNF-α
Matrix:
Human Serum
Assay Range:
IFN-γ: The LLOQ is 1.76 pg/mL (6.24 pg/mL in human serum) and the ULOQ is
938 pg/mL (1010 pg/mL in human serum);
IL-1β: The LLOQ is 0.646 pg/mL (0.656 pg/mL in human serum) and the ULOQ is
375 pg/mL (372 pg/mL in human serum);
IL-2: The LLOQ is 0.890 pg/mL (5.85 pg/mL in human serum) and the ULOQ is
938 pg/mL (947 pg/mL in human serum);
IL-4: The LLOQ is 0.218 pg/mL (0.267 pg/mL in human serum) and the ULOQ is
158 pg/mL (150 pg/mL in human serum);
IL-6: The LLOQ is 0.633 pg/mL (0.797 pg/mL in human serum) and the ULOQ is
488 pg/mL (452 pg/mL in human serum);
IL-8: The LLOQ is 0.591 pg/mL (0.708 pg/mL in human serum) and the ULOQ is
375.000 pg/mL (401 pg/mL in human serum);
IL-10: The LLOQ is 0.298 pg/mL (0.440 pg/mL in human serum) and the ULOQ is
233 pg/mL (250 pg/mL in human serum); IL-12p70: The LLOQ is 1.22 pg/mL (300 pg/mL in human serum) and the ULOQ is
315 pg/mL (250 pg/mL in human serum); IL-13: The LLOQ is 4.21 pg/mL (1.92 pg/mL in human serum) and the ULOQ is
353 pg/mL (312 pg/mL in human serum);
TNF-α: The LLOQ is 0.690 pg/mL (0.404 pg/mL in human serum) and the ULOQ is
248 pg/mL (229 pg/mL in human serum).
Sample Volume:
50 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IFN-γ, IL-2, IL-6, IL-8, IL-10, IL-12p70, and TNF-α -
(Matrix: Human Plasma)
Analytes:
IFN-γ, IL-2, IL-6, IL-8, IL-10, IL-12p70, and TNF-α
Matrix:
Human Plasma
Assay Range:
IFN-γ: 1.328 to 1360.000 pg/mL; IL-2: 1.396 to 1430.000 pg/mL; IL-6: 0.681 to 697.000 pg/mL; IL-8: 0.563 to 576.000 pg/mL; IL-10: 0.351 to 359.000 pg/mL ; IL-12p70: 0.471 to 482.000 pg/mL; TNF-α: 0.355 to 364.000 pg/mL
Sample Volume:
60 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70
Platform:
MSD
IgG1 -
(Matrix: Serum)
Analytes:
IgG1
Matrix:
Serum
Assay Range:
0.430-13.8 µg/mL
Sample Volume:
5 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
ELISA
IgG2 -
(Matrix: Serum)
Analytes:
IgG2
Matrix:
Serum
Assay Range:
0.166-5.32 µg/mL
Sample Volume:
5 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
ELISA
IgG3 -
(Matrix: Serum)
Analytes:
IgG3
Matrix:
Serum
Assay Range:
0.0420-1.34 µg/mL
Sample Volume:
5 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
ELISA
IgG4 -
(Matrix: Serum)
Analytes:
IgG4
Matrix:
Serum
Assay Range:
0.0238-0.760 µg/mL
Sample Volume:
5 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
ELISA
Iguratimod -
(Matrix: Human Plasma)
Analytes:
Iguratimod
Matrix:
Human Plasma
Assay Range:
10-2000 ng/mL
Sample Volume:
50 µL
Anticoagulant:
Sodium Heparin
StorageTemp (oC):
-20/-70/-80
Platform:
LC-MS/MS
IL-13 -
(Matrix: Human Serum)
Analytes:
IL-13
Matrix:
Human Serum
Assay Range:
2.023 pg/mL to 518.0 pg/mL
Sample Volume:
60 µL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IL-15 -
(Matrix: Mouse Plasma)
Analytes:
IL-15
Matrix:
Mouse Plasma
Assay Range:
0.391 pg/mL to 100 pg/mL
Sample Volume:
10 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70
Platform:
MSD
IL-17A -
(Matrix: Human Serum)
Analytes:
IL-17A
Matrix:
Human Serum
Assay Range:
0.23438 - 120 pg/mL
Sample Volume:
75 µL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
Simoa
IL-17A -
(Matrix: Human Serum)
Analytes:
IL-17A
Matrix:
Human Serum
Assay Range:
IL-17A: 65.0 fg/ml - 266000 fg/ml
Sample Volume:
75 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IL-18 -
(Matrix: Human CSF)
Analytes:
IL-18
Matrix:
Human CSF
Assay Range:
0.01 pg/mL to 45 pg/mL
Sample Volume:
50 µL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
SIMOA
IL-18 -
(Matrix: Human Plasma)
Analytes:
IL-18
Matrix:
Human Plasma
Assay Range:
0.01 pg/mL to 45 pg/mL
Sample Volume:
50 µL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
SIMOA
IL-1Beta -
(Matrix: Human Serum)
Analytes:
IL-1Beta
Matrix:
Human Serum
Assay Range:
IL-1Beta: 35.0 fg/ml - 145000 fg/ml
Sample Volume:
75 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IL-2Rα and IL-12/IL-23p40 -
(Matrix: Human Serum)
Analytes:
IL-2Rα and IL-12/IL-23p40
Matrix:
Human Serum
Assay Range:
IL-2Rα: 71.331 to 52000.000 pg/mL; IL-12/IL-23p40: 28.258 to 20600.000 pg/mL
Sample Volume:
60 µL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IL-5 -
(Matrix: Human Serum)
Analytes:
IL-5
Matrix:
Human Serum
Assay Range:
IL-5: 7.8 fg/ml - 32067 fg/ml
Sample Volume:
75 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IL-5, IL-17A -
(Matrix: Human Plasma)
Analytes:
IL-5, IL-17A
Matrix:
Human Plasma
Assay Range:
IL-5: 0.824 to 844.000 pg/mL; IL-17A: 5.957 to 6100.000 pg/mL
Sample Volume:
30 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70
Platform:
MSD
IL-5, IL-17A -
(Matrix: Human Serum)
Analytes:
IL-5, IL-17A
Matrix:
Human Serum
Assay Range:
IL-5: 1.713 pg/mL to 657.8 pg/mL; IL-17A: 12.66 pg/mL to 4860 pg/mL
Sample Volume:
20 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
IL-6 -
(Matrix: Human Plasma)
Analytes:
IL-6
Matrix:
Human Plasma
Assay Range:
0.700 to 2652 pg/mL
Sample Volume:
50 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70
Platform:
ELLA
