Discovery
Medicinal Chemistry Services
Discovery ADME
- Metabolic Stability
- CYP Interaction
- Permeability & Transporters
- Physicochemical Properties
- Protein Binding
Assay Results
Fluoxetine/Olanzapine -
(Matrix: Human Plasma)
Analytes:
Fluoxetine/Olanzapine
Matrix:
Human Plasma
Assay Range:
0.3/0.1-60/20 ng/mL
Sample Volume:
100 μL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70/-80
Platform:
LC-MS/MS
Flurbiprofen -
(Matrix: Human Plasma)
Analytes:
Flurbiprofen
Matrix:
Human Plasma
Assay Range:
40-10000 ng/mL
Sample Volume:
25 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-20
Platform:
LC-MS/MS
Fluticasone Furoate -
(Matrix: Human Plasma)
Analytes:
Fluticasone Furoate
Matrix:
Human Plasma
Assay Range:
0.2-100 pg/mL
Sample Volume:
1 mL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-20
Platform:
LC-MS/MS
Fluticasone propionate -
(Matrix: Dog CSF)
Analytes:
Fluticasone propionate
Matrix:
Dog CSF
Assay Range:
50- 50000 pg/mL
Sample Volume:
50μL
Anticoagulant:
EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Fluticasone propionate -
(Matrix: Dog Plasma)
Analytes:
Fluticasone propionate
Matrix:
Dog Plasma
Assay Range:
10- 10000 pg/mL
Sample Volume:
100 μL
Anticoagulant:
EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Fluticasone propionate -
(Matrix: Dog Synovial fluid)
Analytes:
Fluticasone propionate
Matrix:
Dog Synovial fluid
Assay Range:
0.5- 500 pg/mL
Sample Volume:
50μL
Anticoagulant:
EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Fluticasone Propionate -
(Matrix: Human Plasma)
Analytes:
Fluticasone Propionate
Matrix:
Human Plasma
Assay Range:
5-5000 pg/mL
Sample Volume:
100 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-20
Platform:
LC-MS/MS
Fluticasone propionate -
(Matrix: Rat Plasma)
Analytes:
Fluticasone propionate
Matrix:
Rat Plasma
Assay Range:
20- 20000 pg/mL
Sample Volume:
50 μL
Anticoagulant:
EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Fluticasone propionate /
Fluticasone 17β-carboxylic Acid propionate -
(Matrix: Human Plasma, Minipig Plasma)
Analytes:
Fluticasone propionate /
Fluticasone 17β-carboxylic Acid propionate
Matrix:
Human Plasma, Minipig Plasma
Assay Range:
5/20- 5000/20000 pg/mL
Sample Volume:
400μL
200μL
Anticoagulant:
EDTA
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Fluticasone Propionate/Azelastine -
(Matrix: Human Plasma)
Analytes:
Fluticasone Propionate/Azelastine
Matrix:
Human Plasma
Assay Range:
0.5/2-250/1000 pg/mL
Sample Volume:
50 µL
Anticoagulant:
Sodium Heparin
StorageTemp (oC):
-70
Platform:
LC-MS/MS
Fluticasone Propionate/Formoterol -
(Matrix: Human Plasma)
Analytes:
Fluticasone Propionate/Formoterol
Matrix:
Human Plasma
Assay Range:
1/0.25-500/125 pg/mL
Sample Volume:
0.5 mL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-80
Platform:
LC-MS/MS
Formoterol -
(Matrix: Dog Plasma)
Analytes:
Formoterol
Matrix:
Dog Plasma
Assay Range:
50- 10000 pg/mL
Sample Volume:
100 µL
Anticoagulant:
Heparin
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Formoterol -
(Matrix: Human Plasma)
Analytes:
Formoterol
Matrix:
Human Plasma
Assay Range:
0.5-30 pg/mL
0.5-200 pg/mL
2.5-200 pg/mL
Sample Volume:
500 µL
Anticoagulant:
K2EDTA
K3EDTA
StorageTemp (oC):
-70
Platform:
LC-MS/MS
Formoterol -
(Matrix: Human Urine)
Analytes:
Formoterol
Matrix:
Human Urine
Assay Range:
2.5-200 pg/mL
20-10000 pg/mL
Sample Volume:
2 mL
1 mL
Anticoagulant:
NA
StorageTemp (oC):
-20
Platform:
LC-MS/MS
Formoterol -
(Matrix: Rat Plasma)
Analytes:
Formoterol
Matrix:
Rat Plasma
Assay Range:
0.5- 100 pg/mL
Sample Volume:
50 µL
Anticoagulant:
Heparin
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Formoterol / Desformyl-Formoterol -
(Matrix: Rat Plasma)
Analytes:
Formoterol / Desformyl-Formoterol
Matrix:
Rat Plasma
Assay Range:
50/50- 2000/2000 pg/mL
Sample Volume:
200 µL
Anticoagulant:
Heparin
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
Free IFNɯ -
(Matrix: Human Serum)
Analytes:
Free IFNɯ
Matrix:
Human Serum
Assay Range:
0.5 - 364.5 pg/mL
Sample Volume:
100 µL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
Simoa
Free TNFα -
(Matrix: Human Serum)
Analytes:
Free TNFα
Matrix:
Human Serum
Assay Range:
0.27435 - 200.00000 pg/mL
Sample Volume:
100 µL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
Simoa
Free VEGF-A -
(Matrix: Human Plasma)
Analytes:
Free VEGF-A
Matrix:
Human Plasma
Assay Range:
0.977 to 1000 pg/mL
Sample Volume:
50 µL
Anticoagulant:
CTAD
StorageTemp (oC):
-70
Platform:
Simoa
Frovatriptan -
(Matrix: Human Plasma)
Analytes:
Frovatriptan
Matrix:
Human Plasma
Assay Range:
10-10000 pg/ml
Sample Volume:
100 µL
Anticoagulant:
K2EDTA
StorageTemp (oC):
-70
Platform:
LC-MS/MS
Fulvestrant -
(Matrix: Human Plasma)
Analytes:
Fulvestrant
Matrix:
Human Plasma
Assay Range:
0.2-100 ng/mL
Sample Volume:
100 µL
Anticoagulant:
Lithium Heparin
StorageTemp (oC):
-20/-70
Platform:
LC-MS/MS
G-CSF
GM-CSF
IL-12p40
IL-15
IL-1α
IL-7
MIP-1α
ST2 -
(Matrix: Human Serum)
Analytes:
G-CSF
GM-CSF
IL-12p40
IL-15
IL-1α
IL-7
MIP-1α
ST2
Matrix:
Human Serum
Assay Range:
G-CSF: The LLOQ is 1.25 pg/mL (25 pg/mL in human serum) and the ULOQ is
8500 pg/mL (17000 pg/mL in human serum);
GM-CSF: The LLOQ is 1.0 pg/mL (2.0 pg/mL in human serum) and the ULOQ is
1700 pg/mL (3400 pg/mL in human serum);
IL-12p40: The LLOQ is 10.0 pg/mL (20.0 pg/mL in human serum) and the ULOQ is
25500 pg/mL (51000 pg/mL in human serum);
IL-15: The LLOQ is 3.8 pg/mL (7.6 pg/mL in human serum) and the ULOQ is
2550 pg/mL (51000 pg/mL in human serum);
IL-1α: The LLOQ is 3.7 pg/mL (7.4 pg/mL in human serum) and the ULOQ is
2465 pg/mL (4930 pg/mL in human serum);
IL-7: The LLOQ is 4.0 pg/mL (8.0 pg/mL in human serum) and the ULOQ is
6800 pg/mL (13600 pg/mL in human serum);
MIP-1α: The LLOQ is 31.3 pg/mL (62.6 pg/mL in human serum) and the ULOQ is
1700 pg/mL (3400 pg/mL in human serum); ST2: The LLOQ is 88.0 pg/mL (176 pg/mL in human serum) and the ULOQ is
29750 pg/mL (59500 pg/mL in human serum)
Sample Volume:
60 μL
Anticoagulant:
NA
StorageTemp (oC):
-70
Platform:
MSD
