Complex Diabetes Study
The Centers for Disease Control and Prevention estimates that 25.8 million Americans are affected by
diabetes. That’s more than 8% of the U.S. population. S&P’s Rating Services estimates that the global
diabetes market will grow to 280 million people in the next 20 years, elevating sales of diabetes-related
treatments from $35 billion to $58 billion. As a result, diabetes treatments will remain a growth industry
and an area of continued therapeutic interest for pharmaceutical and biopharmaceutical organizations.
BSEPcyte® fully validated assay platform for measuring BSEP inhibition
Bile salt export pump (BSEP) is responsible for biliary secretion of bile salts, which is the primary driving force for enterohepatic recirculation of bile salts and for maintaining bile flow. BSEP is a 1321 amino acid p-glycoprotein encoded by gene ABCB11 and primarily expressed on the hepatocyte canalicular membrane. Inhibition of BSEP by a diverse range
Consistent with our company’s vision, mission and values, we are committed to pursuing the sustainability initiatives which is an integral part of our business and goes beyond economic, legal or regulatory motives. At Frontage, we have implemented sustainability frame work that promotes long lasting values for our people, customers and all stakeholders.