WEBINAR: Incorporation of Microsampling Techniques in Bioanalytical Assays – Dried Blood Spots (DBS) and capillary microsampling
Date: Thursday, October 18, 2018
Time: 7:00 [PDT] 10:00 [EDT] 15:00 [BST]
Duration: 1 hour
Current pharmacokinetic (PK) and toxicological studies pose an increasing demand on the volume of blood available from study animals, especially when the study involves small rodents. As a response, microsampling techniques, has been introduced into bioanalytical studies.
Dried blood spots (DBS) and capillaries are the two most commonly used microsampling techniques. In this presentation, we present how microsampling can generate high quality bioanalytical data and accurate PK profiling, we also present a unique sample handling method using pre-scored capillaries developed by Frontage and how it overcomes some of the limitations with the conventional capillary microsampling approach.
What will you learn?
- Advantages and challenges of microsampling in bioanalysis
- Case studies
- Unique microsampling methodology, developed by Frontage
- Regulatory perspective
Who will this interest?
- Bioanalytical scientists
- Pharmacokinetics scientists
- Pharmaceutical companies who are interested in performing preclinical and clinical studies utilizing microsampling techniques
Xiaonan Tang is Director in the bioanalytical department at Frontage Laboratories. Xiaonan received his B.S. in chemistry from Beijing Normal University and his PhD in physical chemistry from the University of California, Davis. After two years of Postdoc at the University of Chicago, Xiaonan joined Frontage Laboratories in 2008. Xiaonan is responsible for small molecule bioanalysis under the GLP environment. Xiaonan has extensive experiences in method development, and validation, he has supported over 300 non-clinical (GLP, non-GLP) and clinical studies as principal investigators. Xiaonan is also a key member of the IDBS ELN launching committee at the Frontage Laboratories.
Dr. Yang Lu joined Frontage Lab, Inc. in 2015 and currently servies as Lab Manager of bioanalytical department. Yang received his B.S. in pharmaceutical science and M.S. in medicinal chemistry from Peking University, Health Science Center, Beijing, China. Yang conducted his doctoral research at State University of New York at Stony Brook and got his Ph.D. in chemistry and chemical biology in 2014. Yang’s team is responsible for developing and validating LC-MS/MS based methods for small molecular drug quantitation to support bioanalytical assays in preclinical and clinical studies.