Biomarkers

We have expertise in ultra-sensitive detection capabilities

Iceberg-illustrationA biomarker is a substance used as an indicator of a biologic state. It is a characteristic that can be objectively measured and evaluated as a sign of pharmacologic responses to a therapeutic intervention.

We have ultra-sensitive detection capabilities (Quanterix Simoa) for quantitation in the femtogram/mL range as well as multiplex analysis of various disease categories (e.g. Inflammation, Oncology, Neuroscience, Infectious Diseases, Respiratory, etc.).

  • Available assays across a variety of disease areas
  • Dedicated team with multiplexing platforms

Biomarker validations

  • Fit-for-purpose (FFP) and Exploratory Biomarkers
  • Validation parameters differ depending on the purpose of study and method categories
  • Method validation to support Labelling Claims, Safety, Efficacy

Biomarker assay platforms include LBA, LC-MS, and rtPCR

  • ELISA (single analyte)
  • Meso Scale Discovery (single or multiplex)
  • Quanterix Simoa¬†
  • LC-MS/MS for small molecule and protein biomarkers
  • QuantStudio7 rtPCR