Clinical Biomarkers & Immunogenicity
As noted in our Biologics Services overview, clinical biotherapeutics development demands a high level of expertise and cutting edge resources. Frontage supports your unique needs in this area with advanced methods and technologies for large molecule bioanalytical/immunogenicity and biomarker testing.
Turn to Frontage Biological Services to fulfill your needs for preclinical and clinical Pharmacokinetic (PK) and Immune Anti-Drug Antibody (ADA) testing. Please describe your project needs in general so we can provide greater detail about our services.
In PK testing, Frontage services include:
- Protein therapeutic concentration, and
- WIN NonLin (PK parameters; modeling)
Among our Immunogenicity Services are:
- Antibody screening (ADA, Immunogenicity)
- Antibody titration
- Neutralizing cell-based immunogenicity characterization
Frontage Biologics had developed a range of specialized assays that predict drug efficacy and toxicity. Below is a sample of specialized assays available to you. Our capabilities and technology enable us to develop other specialized assays depending on your needs.
Cell-Based Assays (Preclinical and Clinical)
- In Vitro
- Ex Vivo
- Cell lines, primary cell culture and whole blood components
- Potency assay
- Proliferation assays
- Immune function assays (NAB)
- Custom assay development
Pharmacogenomics & Molecular Biology Testing
In addition to our specialized assays, Frontage offers a host of Biomarker Assays and the capacity to develop new ones upon request.